NEURO410 Lecture Notes - Lecture 8: Caseous Necrosis, Coagulative Necrosis, Fat Necrosis
12 Oct 2016
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Document Summary
Normal cell is in a steady state (homeostasis) Injury is any stimulus bringing changes in cell physiology and/or anatomy internal/external. Adaptation results from the changes in a cell due to reversible injury. Two main events that trigger cells to die: killed by injurious agents, induced to commit suicide. Programmed cell death (pcd): involves dna (ie dna pcd) Cells that die due to external forces mainly undergo necrosis, parthanatos (over activation of. Programmed cell death, apoptosis, occurs normally in developing and mature tissue and therefore can be physiologic or pathologic. Most modes of cell death, particularly necrosis and apoptosis can occur independently, sequentially and/or simultaneously: very rare to have only one of the two. Huge literature of cell death (learned from cancer studies) Other deaths: autophagy, slower cell death (type of apoptosis, mitotic catastrophe) Dramatic and very rapid form of cell death in which every compartment of the cell disintegrates = dirty and explosive.
