BCH210H1 Lecture Notes - Lecture 34: Lipoprotein, Ldl Receptor, Bile Acid

• School: UTSG
• Department: Biochemistry
• Course: BCH210H1
• Professor: Sian Patterson

Document Summary

Transporting fats throughout the body, diet vs. genetics Chapter 9. 4, 5: review questions posted on quercus. Socrative room #317683 (download the app or go to www. socrative. com) Image taken from endo, a. (2008) nature medicine 14, 1050-1052. Lipid transport via lipoproteins: lipoproteins are made either in the intestine (chylomicrons) or liver (vldl or. Lipo-proteins: chylomicrons are made in the small intestine from the diet and mainly contain tags and. Apoprotein 48: vldl is made by the liver and contains the. Apob100 protein: lipoprotein lipase attacks vldl, hydrolyzing. Tags to produce idl ldl: hdl picks up cholesterol (esters) and transports them back to the liver for breakdown, the liver is the main source of lipoprotein packaging and recycling. Hdl is known as the good cholesterol", it travels through the body and picks up cholesterol esters via a lecithin:cholesterol acyl transferase (lcat) enzyme; returning them to the liver for processing and breakdown. The liver"s role in regulating lipoprotein metabolism via.