BIO130H1 Lecture Notes - Lecture 8: Tata Box, Prokaryote, Guanine

• School: UTSG
• Department: Biology
• Course: BIO130H1
• Professor: Mitchell/ Moeder

Document Summary

T(cid:396)a(cid:374)sfe(cid:396)(cid:396)ed to the (cid:1007)" e(cid:374)d p(cid:396)o(cid:272)essi(cid:374)g se(cid:395)ue(cid:374)(cid:272)e o(cid:374) rna (cid:373)ole(cid:272)ule as it e(cid:373)e(cid:396)ges from the rna polymerase: then additio(cid:374)al p(cid:396)otei(cid:374)s asse(cid:373)(cid:271)le (cid:449)ith the(cid:373) to (cid:272)(cid:396)eate the (cid:1007)" e(cid:374)d. Pap (poly-a pol(cid:455)(cid:373)e(cid:396)ase(cid:895) adds a(cid:271)out (cid:1006)00a (cid:374)u(cid:272)leotides to the (cid:1007)" e(cid:374)d p(cid:396)odu(cid:272)ed by cleavage. Poly-a-binding proteins assemble onto the poly-a tail, determining final length of tail. Allow cell to assess whether both ends of an mrna molecule are present before exporting rna sequence from nucleus and translating it to a protein. Rna splicing removes intron sequences from newly transcribed pre-mrnas. Intron and exon sequences are transcribed into rna. Intron sequences removed by rna splicing (before splicing, pre-mrna; after splicing and processing, mrna) Presence of numerous introns in dna allows genetic recombination to readily combine exons of different genes (new proteins able to evolve more easily) Furthermore, transcripts of many eukaryotic genes are spliced in more than one way, allowing the same gene to produce corresponding set of different proteins.