NROB60H3 Lecture Notes - Lecture 8: Neuroglia, The Shortcut, Cerebellum
13 Sep 2016
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Neurotransmitter chemistry: cholinergic neurons, catecholaminergic neurons, serotonergic neurons, amino acidergic neurons. General concepts: three classes of neurotransmitters. A substance is a neurotransmitter if: synthesis and storage occurs in presynaptic neuron, released by presynaptic axon terminal, produces response in postsynaptic cell. Mimics response produced by release of neurotransmitter from the presynaptic neuron. Binds to receptors but instead of inhibiting them, they enhance the actions of naturally occur neurotransmitter: receptor antagonist. Binds to the receptors and blocks the normal action of the transmitter. 5 table 6. 1 the neurophamacology of some receptor subtypes. Receptor subtype: nicotinic, muscarinic o o o. Agonist (for / excitatory: nicotine, muscarine o o o. Two or more transmitters released from one nerve terminal. An amino acid or amine plus a peptide. Acetylcholine (ach: synthesized in all motor neurons, also involved in specific sympathetic and parasympathetic divisions and special circuits of the pns and cns, synthesis requires a special enzyme (chat)
