HLTB22H3 Lecture Notes - Lecture 1: Gp41, Viral Envelope, Endosome
Document Summary
Humoral and cell mediated immunity: humoral b cells creating effector cells. Mediated by molecules in the extracellular fluids that recognize antigens or pathogens in lymph or blood: cell-mediated interactions between cells, apcs, etc. Mediated by specialized cells that respond to antigens presented by abnormal. Hypersensitivity cells or the body: body (cid:396)espo(cid:374)di(cid:374)g to thi(cid:374)gs that a(cid:396)e(cid:374)"t a th(cid:396)eat. Immunodeficiency diseases (id: primary id: resulting from genetic or developmental defect; are present from young age. We are able to usually discern and deal/ cure them from a very early age: secondary id: resulting from environmental cause; can develop at any age and are also (cid:272)alled (cid:862)a(cid:272)(cid:395)ui(cid:396)ed i(cid:373)(cid:373)u(cid:374)odefi(cid:272)ie(cid:374)(cid:272)y diseases(cid:863) Can develop in response to a viral infection at any age. Primary id example scid: scid: severe combined immunodeficiency disease. Immune system so compromised it is essentially absent. So-called bubble babies due to sterile environment that isolates them from pathogens in environment. Stem cell transplants were at very early stages back then.
