PSY397H5 Lecture Notes - Lecture 7: Hitchhiking, Brain-Derived Neurotrophic Factor, Integrin
Document Summary
Postsynaptic depolarization precedes presynaptic neurotransmitter release synaptic depression occurs: s1 before s2 = excited post synaptic terminal, s2 before s1= reduction of epsp. Other forms of synaptic plasticity: ppf- pre pulse facilitation. Essay: 5 pages including (intro discussion abstract if you want) title page + references not included in. 5 pages: 12 font, double spaced, apa references, review a few paper summarize results and have a critical analysis, must be discussed as your. Own opinion or your own critical thinking: 3-10 references are preferable. ***shape of pre/post synaptic connection cells will also change through modi cation. Injection of pkc inhibitor disrupts e-ltp: pkc- causes phosphorylation of target proteins, if a peptide is on the surface of pkc, kinase is blocked so will not phosphorylate target proteins, therefore late phase will be affected. Depotentiation ltd: ampa phosphorylation: induce ltp then s831 gets de-phosphorylated, convert ltp to ltd then s845 gets de-phosphorylated.
