BIO341H5 Lecture 3: Lecture 3
Document Summary
10^4 is too many mutations, so has to verified as true mutations use pcr. Inside of red difference to outside: change in loh, loss of heterozygosity: blue another loh in a single chromosome and snp sites that have become homozygous, gene conversion. Spectrum in spontaneous, mutation and infer what happened in the past, taking into account the spatial context: only expect one change on a specific base over many generations. Fungus avoids using cell divisions on its germ lines, lower mutation rate increase in repair enzymes.
