BIO315H5 Lecture Notes - Lecture 9: Nfat, Secretion, Inner Membrane
Document Summary
Intracellular compartments of an animal cell: cell is highly compartmentalized structure with subcellular compartments. 4 families of intracellular compartments based on topological (same) space: nucleus and cytosol, vesicles that are part of the vesicular and endosecretory pathways such as er, Golgi, endosomes and secretory vesicles: mitochondria, plastids. In all cases, need sorting signals as well as proteins that recognize these signals. If from the cytosol to the membrane compartments, it is thru transmembrane transport: once in a membrane compartment, to go from one membrane compartment to another is thru vesicular transport. Nucleocytoplasmic transport: nuclear envelope is a double membrane structure that has an inner and outer nuclear membrane. Inner and outer membrane are continuous with each other: the outer membrane is actually continuous with er membrane. Just because they are continuous does not mean they are the same because they are distinct based on the proteins that are embedded or expressed.