BIO310H5 Lecture Notes - Lecture 15: Capillary Pressure, Muscular Layer, Arteriole

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10 Feb 2018

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To maintain the blood pressure, but not to the level when the blood leaves the heart, the arteries as they travel away from the heart, they will be able to maintain the pressure. Arterial system: because the arteries have muscular layers, they will be able to (3 on slide) If blood pressure is lower, the blood pressure will be lowered, the smooth muscle will be stimulated so there will be contraction. If the blood pressure is higher, the smooth muscle will relax and there will be dilation, this will reduce the blood pressure. Capillary pressure: there will be reabsorption after the filtration, but the reabsorption is less than what was filtrates. In the lymph nodes, there is elimination of foreign materials, for example cancer cells. If lymph nodes are swollen, the cancer cells are trapped there. Lymphatic vessels will just go back and drain into the major veins.

Related Questions

QuestionGroup: #37 CNS

Assigned as

Homework

Which parts of the brain contribute to our social behavior?

Orbitofrontal cortex

Mirror neurons

Amygdala

All of these are correct

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QuestionGroup: #38 CNS2

Assigned as

Homework

Part of the explanation of long term memory is which of the following?

Long term potentiation between neurons and muscle cells

Long term potentiation between neurons

Short term translation

Long term transcription

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QuestionGroup: #39 PNS

Assigned as

Homework

The somatic component of the peripheral nervous system has which of the following characteristics?

It controls the smooth muscle in the blood vessels so that blood vessels can vasoconstrict or vasodilate

It controls the autonomic nervous system so it indirectly controls heart rate

It controls your skeletal muscle so you can answer this question by pushing on the keyboard

It controls the smooth muscle in your intestinal tract so it controls peristalsis

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QuestionGroup: #40 Smooth/skeletal

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Homework

Which of the following is NOT a part of a skeletal muscle cell?

Motor neurons

Nuclei

Sarcomeres

Actin

Myosin

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QuestionGroup: #41 Cardio

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Homework

Which part of the circulatory system has the highest pressure?

Veins

Capillaries

Arteries

Aorta

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QuestionGroup: #42 Cardio2

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Homework

Where do the electrical signals originate in your heart?

SA node

Internodal tracts

His-Purkinje System

AV node

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QuestionGroup: #43 Blood pressure

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There was a horrific traffic accident and you run to help the victims. You feel a pulse from his carotid artery ,however the medic comes along and gets no blood pressure as he measures it from the arm. He claims the victim is dead. You think which of the following?

Medic is not correct since it is the difference between heart rate and blood pressure that determines life. No heart rate only means tha the sympathetics have stopped vasoconstricting the blood vessels.

Medic is correct since it is common to not have a blood pressure of 120/80 and no pulse due to stress as was discussed in class.

Medic is incorrect since there is a pulse. This means the person is still alive.

Medic is correct since there is no blood pressure there is no life.

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QuestionGroup: #44 Blood pressure2

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Which side of the capillary bed has the higher oncotic pressure?

venous and lymph

arterial and lymph

lymph

venule side

arterial side

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QuestionGroup: #45 Capillaries

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If the hydrostatic pressure is higher in the interstitial space rather than the capillary, which of the following will occur?

(2),(3)

(1),(2),(3)

(3) Decreased hydrostatic pressure in the arterial end of the capillary

(2) Decreased hydrostatic pressure in the venous end of the capillary

(1) No change in the hydrostatic pressure since this pressure is maintained regardless of external pressures.

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QuestionGroup: #46 Respiration/ ventilation

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The left atrium is damaged and is generating a great resistance to blood coming from pulmonary vein. What happens due to this pressure?

Back up of blood in the pulmonary artery which causes pulmonary capillary edema

Generation of back flow into the inferior vena cava

Generation of coronary artery edema

Back up of blood in the pulmonary vein which causes pulmonary capillary edema

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QuestionGroup: #47 Respiration/ventilation 2

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Edema in the pulmonary circulation refers to which of the following?

additional fluid in the trachea

additional interstitial fluid

additional surfactant

additional capillary fluid

additional intracellular fluid

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QuestionGroup: #48 Cell communication

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What is the definition of a signaling pathway?

All the proteins in the nucleus

All the cell molecules in the mitochondria

A group of genes that control mitosis

A specific chemical pathway that is activated by the ligand/receptor complex.

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QuestionGroup: #49 Hormone/ menstruation

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Which hormone directly causes ovulation?

Follicle stimulating hormone

Lutenizing hormone

Progesterone

Estrogen

All of these

True of False: Freshwater environments have a higher concentration of oxygen than saltwater environments.

QUESTION 2 If the difference in partial pressure of gas on either side of the barrier to diffusion is 0, which of these events will occur?

The area for gas exchange will increase to accommodate this similarity.

The constant for diffusion will decrease.

The rate of diffusion will be 0.

The distance thickness of the barrier to diffusion will also be 0.

QUESTION 3 On the x-axis of the oxygenâhemoglobin equilibrium curve is the partial pressure of oxygen in tissues. Which type of blood is most likely to be represented by the right-hand side of the axis? (Hint: the oxygen-hemoglobin equilibrium curve is figure 45.14 in your book on pg 913)

blood found in the left ventricle

blood found in the right atrium

blood found in the superior vena cava

blood found in the inferior vena cava

QUESTION 4 Which of these is an example of pulmonary circulation?

Blood is pumped from the right ventricle to the lungs.

Blood is pumped from the left ventricle to the aorta.

Blood is pumped from the aorta to the cardiac vein.

Blood is pumped from the inferior vena cava to the right atrium.

QUESTION 5 O2 will diffuse from blood to tissue faster in response to which of the following conditions?

an increase in the PO2 of the tissue

a decrease in the PO2 of the tissue

an increase in the thickness of the capillary wall

a decrease in the surface area of the capillary

QUESTION 6 Which of the following promotes oxygen release from hemoglobin?

a decrease in temperature

a decrease in carbon dioxide levels

a decrease in pH

a decrease in carbonic anhydrase

QUESTION 7 How does the medulla oblongata sense the amount of carbon dioxide in the blood?

A. Carbonic anhydrase produced by cells performing cellular respiration is exported and travels though the blood, and binds to a receptor on the medullary respiratory center, which causes a signal amplification resulting in a change in gene expression which results in the production of proteins that will cause the diaphragm to contract

B. CO2 produced by cells performing cellular respiration reacts with blood plasma for form an acid, which increases the pH of the blood, which causes the medullary respiratory center to contract the diaphragm

C. CO2 produced by cells performing cellular respiration reacts with blood plasma for form an acid, which decreases the pH of the blood, which causes the medullary respiratory center to contract the diaphragm

D. A and B

E. A and C

QUESTION 8 Which of the following parts of the lung are considered "dead space"? A. The alveoli B. The trachea C. The bronchi D. B and C E. All of the above

QUESTION 9 Which of the following blood vessels have the thinnest walls?

arteries

arterioles

capillaries

venules

veins

QUESTION 10 How does the interstitial fluid return to the bloodstream?

A. Interstitial fluid flows into the capillary where the osmotic pressure driving fluid into the bloodstream is greater than the blood pressure driving fluid out of the blood

B. Interstitial fluid flows into the capillary where the blood pressure driving fluid into the bloodstream is greater than the osmotic pressure driving fluid out of the blood

C. Interstitial fluid leaves the tissue via lymphatic ducts and travels through the lymphatic system, which returns the fluid to the veins. D. A and C

E. B and C

QUESTION 11 True or False: When an electrocardiogram (EKG or ECG) shows a flat line (aka asystole), medical personnel will restart the heart using a defibrillator.

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1) The neurotransmitters acetylcholine and norepinephrine are digested by enzymes that are located at the axon synapse or within the axon terminal of the neurons.

a)What are the names of these different types of enzymes?

b)Where are they located and what is the result of their enzymatic activity?

2) Explain how the Investigational New Drug process works as well as the four different phases of clinical trials. Why are some drugs still taken off the market after approval by the FDA?

3) A single IV injection of 100 mg drug with a half-life of 4 hours is administered to a young adult.

a) Plot drug concentration versus time on a graph making certain to clearly label.

b) How long will it take to eliminate > 95% of the drug?

c) If the volume of distribution is 4L, what is the clearance of the drug?

4) Many drugs are metabolized in the liver through the microsomal metabolizing system.

a) What specific enzymes are involved in this metabolism?

b) What are the main functions of these enzymes?

c) What are some factors that can contribute to individual drug metabolism variation? Explain.

5) Think of an emergency situation requiring immediate and intense physical exertion.

a) List as many body organs as you can and predict the desired level of activity [increased or decreased].

b) Which neurotransmitter would produce these effects and through what receptors?

6) It is interesting that a drug can produce a therapeutic effect and an undesired side effect in one situation, and that the same drug side effect may be considered a therapeutic effect in another situation. Explain this phenomenon using the drug promethazine as an example.

7) A patient brought into the emergency room is experiencing severe hypotension. Blood pressure reads 90/50.

a) What class of drugs is indicated for treatment and why?

b) What precautions should be observed when these drugs are administered?

c) What would be the first indication that too much drug has been administered?

8) Only certain drugs are capable of crossing the blood brain barrier.

a) How is the blood brain barrier different than barriers found in other areas of the body? Be specific.

b) What properties of drugs will make it more likely to cross the blood brain barrier? Explain your answers.

9) A 32-year-old, presents to the Emergency Department by ambulance with vomiting, confusion, salivation, and respiratory distress. The patient states that he was feeling fine until today when I started getting ill. He then vomits. During a physical exam you record the following information: Heart rate 45; Blood pressure 90/60; Respiratory rate 25; Temperature 36.6C; Pupils constricted. During your exam, 4 more ambulances arrive with patients with similar symptoms. You find out they were all riding in the same care on the Red Line when they began feeling ill.

a) What do you feel is happening and why?

b) Would you expect their symptoms to improve over time? Why or why not?

c) What drug would you prescribe to treat these patients and why?

10) Betty has diabetes and asthma. She also has developed high blood pressure, for which doctor just prescribed propranolol. One of your duties as a physicianâs assistant is to make sure patients are not prescribed drugs that are contraindicated because of other health problems.

a) What should you tell the doctor about Bettyâs prescription for propranolol and why?

b) Is there a more appropriate drug for Betty? Explain you answer.

BIO310H5 Lecture Notes - Lecture 15: Capillary Pressure, Muscular Layer, Arteriole

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