BIO202H5 Lecture Notes - Lecture 7: Myelin, Peripheral Nervous System, Schwann Cell

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4 Mar 2019
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Action potential is generated at the initial segment. First segment of axon is depolarized to +30mv. Depolarization causes spreading of the local current that depolarizes the next axon segment to threshold. When depolarization of the next segment reaches the threshold > -60mv. Action potential is generated and when +30mv is reached the na+ As the next segment is getting depolarized, the first segment is undergoing channels close repolarization. Because the na+ channels have closed and the k+ channels have opened. The first segment cannot depolarize again until the repolarization has completed. The action potential continues to travel down the axon. Myelin sheath is produced by the schwann cells in the peripheral nervous system. Signal transduction is faster in salutatory myelinated axons. Action potentials only happens at the node of ranviers. Action potential spreads quickly through the internodes and slowly through the nodes. A single axon can be both myelinated and unmyelinated.

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