BIO153H5 Lecture Notes - Lecture 2: Tiger Salamander, Limb Development

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Biology Lecture 2.1
What triggers new species?
Changes in Rate & Timing of gene expression
o Heterochrony and the role of paedomorphism
Paedamorphosis: Sexually maturing early
Tiger salamander: metamorohases from larva= adult reproduces
Breeding for particular appearance
o Initial reason was to achieve certain traits. Eg: bulldogs were bread to have
stronger jaws, short flat face.
o All mammalian animals adapt fast growth.
o Peramorphasis: physically maturing early
Cope’s Rule: overall increase in size
Body size and speciation
o body size usually increases from early to later forms in a lineage
Hox genes: (regulatory & evolutionary role)
o The hox genes tell the dna how to sequence the change
o Nausea in pregnant women: it controlled the nausea, but it interfered with the
proteins responsible for the limb development.
Recognised that regulatory genes were responsible for such problems.
Hox Genes are arranged in segments where the first one is the original, and the rest
ones are just the replicate of it.
NOTES
Plants have a genetic material called MADS which are specific hox genes
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