HSS 3305 Lecture Notes - Lecture 4: Mast Cell, Glycoprotein, Interferon

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Specific defenses and acquired immunity: antigen recognized as a foreign element, cell mediated immunity would cause activation of lymphocytes, humoral immunity would cause activation of antibodies. Immune response: pathogens trigger both nonspecific and specific responses (sneezing, crying, etc) to not let pathogens in. Immunological specificity: every virus, bacteria, cell, molecule has a unique structure that can be recognized and differentiated. Characteristic, unique part of antigen, usually few amino acids or carbohydrate residues. Specialized section of the antigen which will interact with immune system components (b cells, t cells and antibodies) Immune response must distinguish between self and non-self: all (cid:272)ells (cid:272)arr(cid:455) disti(cid:374)(cid:272)ti(cid:448)e (cid:373)ole(cid:272)ules that disti(cid:374)guish as (cid:862)self(cid:863, antigen has epitopes that have lock and key formation with antibody. Immune response not normally directed to tissues that carry self marker. There is a lag time between exposure and maximal response. Exposure results in immunologic memory types of acquired immunity: acquired immunity: developed after contact with a pathogenic microorganism.

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