HSS 3305 Lecture Notes - Lecture 2: Endometrium, Respiratory Epithelium, Optio

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Review cell biology: build on molecular/ cell biology foundation to understand pathophysiology of disease, understanding, gene biology. Rna: homeostasis, ph, volume, os(cid:373)olarit(cid:455) , cell environment communication, cell function tissue. Genotype, phenotype: phenotype: biologically trait not secondarily acquired if transmissible between different generations, phenotype is heritable, likely to have a genetic basis called genotype, genotype: genetic basis for hereditary phenotype, environment-gene interactions. Bifunctional adaptor molecule which matches mrna with amino acid rrna. Part of enzymatic complex which directs polypeptide assembly. Chromosomes: dna arranged in chromosomes, coding and non-coding dna. Centromeres, telomeres: non-coding dna (ie. sequences do not code for particular phenotype) Long stretches that make up the centromere (in middle of chromosome) Long stretches at the ends of the chromosome, the telomere: telomeres keep the ends of the various chromosomes in the cell from accidently becoming attached to each other, regulate cellular replicative lifespan.

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