HSS 1100 Lecture Notes - Lecture 5: Gram-Negative Bacteria, Gram-Positive Bacteria, Exotoxin

• School: University of Ottawa
• Department: Health Sciences
• Course: HSS 1100
• Professor: Franco Pagotto

Document Summary

Gram positive bacilli: all gram positive are purple. Exotoxins are made of 3 proteins: edema factor (ef, protective antigen (pa, lethal factor (lf) Separately are not toxic but together are lethal pxo2 plasmid encodes capsule genes protects and is made of protein requires both plasmids for virulence virulence degree of pathogenicity. Aboriginal people are at risk for botulism allow food to ferment underground, there is less oxygen and allows spores to ferment in our gi tract. Infant botulism honey contamination with spores (pasteurized honey is not enough to get rid of spores) Good uses of botulinum: botox type a, treat eye muscle disorders, uncontrollable blinking and misaligned eyes (strabismus, excessive sweating, chronic pain, muscle spasms, jaw tensions, migraine headaches. Clostridium perfringens anaerobic: gas gangrene seen in soldiers in battle. 2 classes: wounded infection cellulitis (necrotic skin, clostridial, treated with oxygen.