BPS 2110 Lecture Notes - Lecture 3: Etanercept, Generic Drug, Headache

• School: University of Ottawa
• Department: Biopharmaceutical sciences
• Course: BPS 2110
• Professor: Alain Musende

Document Summary

We use the most drug in agriculture with livestock, fish farms (example of fish farms in bc), combat this by using a lot of antibiotics. This is a real contributor for antibiotic resistance. This does(cid:374)"t (cid:373)ea(cid:374) the (cid:373)ost pres(cid:272)ri(cid:271)ed (cid:271)ut just ge(cid:374)erated the (cid:373)ost i(cid:374)(cid:272)o(cid:373)e: lipitor. This is a dense ring, a lot of drugs we use have substituents. This has come about because of how our bodies have grown over time. There are only so many times you can design something, because it must be open and exposed. When you have a deep valley / pocket you need a ring that can fit in the pocket. This will constitute a significant amount of the drug. Will talk about ways for things to bind to one another. Generally, (cid:449)e do(cid:374)"t use a (cid:272)o(cid:448)ale(cid:374)t i(cid:374)tera(cid:272)tio(cid:374) to keep it i(cid:374) pla(cid:272)e: nexiam. Proton pump inhibitor, decreases the amount of acid in the stomach, called the purple pill.