BIO 3302 Lecture 4: LECTURE 4 – CONTROL AND REGULATION OF CIRC
13 Dec 2016
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Lecture 4 control and regulation of circ. The single endothelial layer wall of a capillary. Smooth muscle in the walls of the largest veins. Priority system: brain, heart & lungs/gills vs. gut, liver, muscles: given priority if there"s a limited flow of oxygen. Ischemia(lack of blood flow), hyperemia (lower blood flow)(active, reactive happens after a period of ischemia) Ischemia lack of blood flow: hyperemia higher than normal blood flow caused by active hyperemia high metabolic activity and reactive hyperemia that happens after an event of ischemia. E(cid:454)a(cid:373)ple: ra(cid:455)(cid:374)aud"s s(cid:455)(cid:374)dro(cid:373)e: cold-induced ischemia with reactive hyperemia upon re-warming. Higher than normal blood flow after ischemia. Alpha 1 are common in viscera / internal organs (gut, gonads etc) Cause smooth muscle to relax muscles dilate. Circulating catecholamines (adrenaline) no basal tone. 2-adrenoreceptors act through camp pathway and activate calcium pumps that lower ca in cytoplasm causing smooth muscles to relax muscles dilate.
