BIO 3170 Lecture Notes - Lecture 9: Ciii-Dt, Integrase, London Academy Of Music And Dramatic Art

• School: University of Ottawa
• Department: Biology
• Course: BIO 3170
• Professor: Oddette Laneuville

Document Summary

Does it enter lysogenic mode?does it enter lytic mode: lytic phage genome is copied and expressed lysed and released to infect, lysogeni is when it integrates (however it can be reversed) If you reach lytic then you cannot reverse because bacteria has died. Viruses (cid:374)eed a host (cid:271)e(cid:272)ause it does(cid:374)"t ha(cid:448)e a(cid:374) rna pol(cid:455)(cid:373)erase. The the host is well nourished and divididing. It enters lytic: moi multiplicity of infection. High moi bacteria is immune to infection. The head and tail genes encodes for the capsid. At the top there are repressors antiterminators etc: cro and c1 are two repressors, n and q are antiterminators (allws rna polymerase to read through terminator sequences, phage la(cid:373)da does (cid:374)ot ee(cid:374)(cid:272)ode rna pol(cid:455)(cid:373)erase!!! That"s (cid:449)h(cid:455) (cid:449)e (cid:374)eed the rna polymerase from ecoli bacteria: no genes for ribosomes too. Pl and pr are the strongest promoters and are the first promoter that rna polymerase will use for tranctiption.