BIO 3124 Lecture Notes - Lecture 11: Terpenoid, Endomembrane System, Biofilm

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20 Dec 2018
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Membrane composition: peptidoglycan (-) cells: nam directly cross link and thin layer with lps (+) cells: 90% composition. S-layer: withstand osmotic pressure, serves as cell wall wall for some. Fimbriae: short bristle-like, attach to surfaces and other cells. Slime layer: loosely attached to cell wall, help attach to surface, biofilm and protect against dehydration. Capsule: outside of cell wall, protecting from getting engulfed by phagocytic cells. Flexible whip, 9+2: cilia: cover entire surface. Need tfs to recruit rna pol, chromatin modifers. Infectious, acellular, obligate intracellular misfolded proteins surrounded by a protein capsid. Surrounded by phospholipid membrane studded with viral glycoproteins. Dna or rna genome small, circular, ssrna spontaneously misfold/mutated and. Nucleocapsid (capsid + nucleic acid) smallest known pathogens few enveloped plant or bacterial viruses because of cell walls exit animal cells more easily. Entry: viral surface proteins cause localized mechanism membrane disruption, viral protein conformational change that open a channel.

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