BIO 1140 Lecture Notes - Lecture 5: Cytoskeleton, Fibronectin, Colchicine

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Animal cells: cell-cell connections 4: gap junctions 4, tight junctions 4, adhesive (anchoring) junctions 5. The extracellular matrix (ecm) of animal cells 6. For greater depth, read selectively from the following articles: Provides rigidity and protection, regulates permeability: hydrating matrix with reinforcing fibers cellulose microfibril. Cellulose is unusual because cellulose is synthesized on the outside of the cell: produced by cellulose synthase complex in plasma membrane on outside of cell. Patterns of cellulose microfibrils are determined by mts which determine where synthases can move: movement of cellulose is guided by microtubules found under them. Because mt"s controls movement of complexes that produce cellulose, and inhibiting growth of mt with colchicine would thus effect the pattern of cellulose fibrils in the cell wall. Cell wall makes it difficult for cells to communicate with each other. A variety of types: gap junctions. Similar to plasmodesmata of plant cell, see full description below: tight junctions.

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