BIO 1140 Lecture Notes - Lecture 6: Fas Ligand, Cytochrome C, Apaf1
23 Jan 2018
School
Department
Course
Professor
Document Summary
Growth- eliminating unwanted cells from a variety of tissues. (tissues between fingers and toes). Cell death is programmed and regulated by the cooperation of a variety of signaling pathways, some act to induce cell death while others act to promote cell survival. Apoptosis- programmed death- well arranged and doesn"t cause any damages to other cells. Chromosome condenses and the nucleus breaks up into tiny pieces. Cell itself shrinks and breaks down into membrane enclosed components. Content is phagocytized by neighbouring cells and macrophages. - no swelling. Ced 3 and ced 4- promote apoptosis- both are necessary, can"t go on without one. Ced 9- prevents apoptosis- isn"t any then large amount of cell death, too much results in the necessary elimination of cells to not occur. Caspases- a bunch of proteases that bring cell death. Cysteine (c) particles at their active site and they split after the aspartic acid (asp) particles are in their substrate proteins.
