BIO 1140 Lecture Notes - Lecture 14: Aminoacyltransferase, Aminoacylation, Transfer Rna

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Enhancers recognized by activators found only in specific cell types. In addition to tic; activators and repressors control which genes are expressed and the rate at which transcription occurs. Whe(cid:374) rna is(cid:374)"t i(cid:374) the (cid:396)ight place the(cid:396)e is a (cid:373)echa(cid:374)is(cid:373) that will cha(cid:374)ge the expression of those genes. They make mirna (some spliced out introns) to correct the rna. Rna interference is best described as the phenomenon of silencing a gene post-transcriptionally by. Mirna or sirna binding to part of the mrna by complementary based paring. Micro rnas are important for regulation of gene expression they form mirisc (mirna induced silencing complex) this halts translation and/reduces available mrna. Post-transcriptional will produce a semi-loop structure called precursor-mirna a dicer enzyme moves the loop and the protein complex binds to double-stranded rna. Enzyme in the protein complex degrades one of the rna strands leaving mirna. Mirna in the mirisc binds to target (cid:373)rna that have (cid:272)o(cid:373)ple(cid:373)e(cid:374)ta(cid:396)y (cid:271)ase se(cid:395)ue(cid:374)(cid:272)es i(cid:374) the 3" utrs.

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