BIO 1140 Lecture Notes - Lecture 7: Prenylation, Spectrin, Photobleaching

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violetseal552

30 Jan 2017

School

University of Ottawa

Department

Biology

Course

BIO 1140

Professor

Caroline Petit- Turcotte

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Document Summary

**last new material for midterm! next class is a q&a!! * membrane potential has been postponed to the signal transductions unit- not on midterm. What properties does the protein need to be in the membrane: polar and hydrophilic inside - allows transport through the inside into the cell, non polar and hydrophobic outside - allows imbedding into membrane. Why are proteins not bound covalently: too hard to break when the membrane needs to change. Span the whole membrane ( can be >1 time) The portions on the inside are non polar near fatty acid chains / hydrophobic and polar near the centre to interact with the tails. The portions on the outside are hydrophilic. N or c terminus can face inside or outside cell. Eg. ion channels, transporters, receptors: peripheral. Proteins that interact with the membrane with integral proteins. Extracellular - will be useful for adhesion and recognition (gpi) Intracellular - involved in mediating cell division and growth.

Related Questions

During active transport in the neuron, the outside of the cell is _________________ and the inside is _______________.

positive, negative

more positive, less positive

more negative, less negative

negative, positive

In active transport, _____________ provides the energy to move molecules against their concentration gradient.

nucleus

potassium

sodium

adenosine triphosphate

________________ proteins can change shape when moving substances across the membrane.

Proteins that can be open or closed, based on different conditions, are called ___________.

bypass proteins

channel proteins

selective proteins

gated

Tunnels that allow charged ions to move easily across the plasma membrane without the use of energy are called ____________________.

channel proteins

glycolypipd proteins

phospholipid proteins

carbohydrate chains

____________ and ____________ make it easier for molecules to move across the plasma membrane.

small, negatively charged

small, positively charged

small, no charge

large, negatively charged

large, positively charged

Cellular biology answer check. please check if my answers arecorrect or not.

1) The concentration of ions inside a cell is the same as theirconcentration outside of the cell. True or false? (i chose falsesince having equilibrium inside a cell is bad)

2) Membrane transport proteins...

a)...transport membrane potentials between cells

b)	...transport membranes from the ER to the Golgi

c)	...are made up of phospholipids

d)	...transport molecules across membranes

i chose d

3)The electrochemical gradienttakes into account:

a)	The concentration of solutes on either side of themembrane.

b)	The overall charge on either side of the membrane.

c)	Both of these.

i chose C. (although i am sure that overall charge matters, Iwasn't sure if concentration of solutes are taken account.)

4) If no energywere expended by an animal cell:

a)	Both gradients would be depleted

b)The K+ gradient would maintain itself.

c)	None of these

d)	The Na+ gradient would maintain itself.

I chose d) mainly because I think Na+ gradient exist in animalcell and not K+ gradient.

5) Which of the following is a true statement aboutactin?

a)	Once actin has polymerized, it never depolymerizes.

b)	Actin is a transmembrane protein.

c)	Actin can form branched networks.

d)	Actin filaments are organized into hollow tubes.

I chose c. can't explain why.

6)Ion channels:

a)	Form a hydrophobic channel through the membrane

b)	Have filters that let sugars through

c)	Are selective for particular ions (only the

taupeshark376

6. True or false

a_______ Nuclear pore complexes are specialized so that some mediate import and others mediate export

b_______ Membrane-bound and free ribosomes, which are structurally and functionally identical, differ only in the proteins they happen to be making at a particular time.

c_______ Some proteins can be made as either free or membrane-bound proteins. They have the same mRNA but different splicing and poly-adenylation patterns

d_______ a protein that does not have a sorting signal will be tagged for destruction by ubiquitin

e_______ when the hydrophobic signal peptide emerges from the ribosome, it is bound by SRP, which causes a pause in protein synthesis. Synthesis resumes when the ribosome with a bound SRP then binds to the SRP receptor on the cytosolic surface of the rough ER.

f________ A protein cannot leave the ER unless it is correctly folded

g________ All of the glycoproteins and glycolipids in intracellular membranes have their oligosaccharide chains facing the cytosolic side, and all those in the plasma membrane have their oligosaccharide chains facing the outside of the cell.

BIO 1140 Lecture Notes - Lecture 7: Prenylation, Spectrin, Photobleaching

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