BIO 1140 Lecture Notes - Lecture 12: Hayflick Limit, Telomerase, Aneuploidy
Document Summary
Some cells divide very often (roots (plants), epithelium (skin/intestines), etc. Some do not divide in adults (red blood cells, muscles, most neurons) During the 70"s the big question was "how does the cell know what to do and when to do it?: a lot of the answers came thanks to being able to understand many signal transduction pathways. Cancer, apoptosis, mutations, many consequences and failsafe mechanisms. In a clock example, there are 24 hours in a cells life, you start interphase which lasts 23 hours. Interphase takes most of the time and is divided into 3 important moments: g1: Start increasing the amount of enzymes and proteins that are going to be involved in the subsequence phases. Use atp synthase by increasing the number of mitochondria and number of atp production in those mitochondria (oxidative phosphorylation or cellular respiration) o. This is where dna replication occurs: g2: