BIO 1140 Lecture Notes - Lecture 6: Phosphatidylserine, Small Cell, Intermediate Filament
27 Sep 2016
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Document Summary
The side of an organ or organism depends on the total cell mass; the cell number must be controlled. Cells grow in size and number but in some point there must be a limit or an end. There needs to be a way to prune: get rid of unhealthy or insufficient cells. At some point the absence of growth factors tell the cell to stop growing: mitogens (cell division) o. The absence of survival factors signals now the cell needs to die. Cell cycle checkpoints: during the cells life cycle, it undergoes a series of steps o. There are some molecular checkpoints along the way that verify the cell is healthy, the. Dna is not too damaged and that the cell can actually divide: at these checkpoints there is opportunity to repair the cell or if the damage is too great, it will send the cell to die.
