APA 1122 Lecture Notes - Lecture 4: Dracunculus Medinensis, Helminths, Mebendazole
12 Jun 2016
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Shown to cause cognitive impairment in children (see notes for references) Elimination of helminths shown to improve outcomes in cognition. Many studies show high truancy among infected children. 3 types: roundworms (nematodes, tapeworms (cestodes, flukes (trematodes) Hookworms: come in through skin, coughed up and swallowed, lives in intestine. Treated with mebendazole which kills worms but not eggs. Good news for humans, bad news for nematodes. In 1986, 3. 5 million cases of guinea worm (dracunculiasis) in 20 endemic nations in asia and africa. Number of cases in 2012 542 (99. 98% reduction) Disease remains in south sudan, chad, mali and. Regular contact with the ground (as all children have) makes it inevitable that the hands that have been on the ground will eventually be in the mouth. Fecal matter is common in the dust and dirt: lumbricoides affects 1 b world-wide. Eggs can persist in soil for 10 years.
