ANP 1107 Lecture Notes - Lecture 13: Vasodilation, Cortisol, Osteoclast

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Renal system: the role of kidneys in fluid and electrolyte balance. Water occupies two main uid compartments within the body. Plasma: the uid portion of blood (20% ecf) Interstitial space: uid in microscopic spaces between tissue cells (80% ecf) Water serves as the universal solvent in which a variety of solutes are dissolved. Solutes may be classi ed broadly as electrolytes and non electrolytes. Non-electrolytes have bonds that prevent them from dissociating in solution. For this reason, no electrically charged species are created when non-electrolytes dissolve in water. Electrolytes are chemical compounds that do dissociate into ions in water. Electrolytes have much greater osmotic power than non-electrolytes because each electrolyte molecule dissociates into at least two ions. In ecf: chief cation is sodium and chief anion is chloride. In icf: chief cation is potassium and chief anion is hydrogen phosphate. Sodium and potassium ion concentrations in ecf and icf are opposite.

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