PHRM 311 Lecture : 5_GI_Therapeutics_of_Nausea_and_Vomiting_(Part_4)
Document Summary
Therapeutics of nausea and vomiting (part 4) An acute inflammation of the lining of the stomach and intestines typically viral in nature (e. g. norwalk virus, rotavirus, enteric adenovirus) Transmitted primarily by the fecal-oral route (also via aerosolization, contact) Symptoms (non-specific): sudden onset of diarrhea vomiting. No antiemetic shown to be superior to any other. Choose based on availability, cost, convenience, previous use/response, adverse effect profile, and patient preference. Associated with a group of unpleasant feelings that develops after drinking too much alcohol (aka hangover) Genetic mutation in alcohol dehydrogenase can predispose individuals to severe hangover symptoms. No antiemetic medication shown to work well not well studied. Choosing light or clear coloured beverages over darker ones (fewer congeners) Toxicity observe for the most common adverse effect(s) Select a medication that works antagonistically to the neurotransmitter/pathway. Consider patient preferences (i. e. routes, what has previously worked/not worked, adverse effects of the medication)
