PHAR 460 Lecture Notes - Lecture 3: Laxative, Sildenafil, Cyp3A4
16 Sep 2016
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Document Summary
Framework for thinking critically about nhps: assess issues/ Helps uncover beliefs, expectations and misinformation so that you can provide accurate evidence. Clinical practice guidelines > meta-analysis systematic reviews > rcts > cohort studies > case controlled studies > case report/case series, narrative reviews, expert opinions, editorials > animal/lab studies. Chronic condition but mild-moderate signs and conditions. Not delaying access to a better alternative. Botanicals need to be fully described to duplicate studies and to be able to select the same product off the shelf. Provide proprietary product name or extract name and name of manufacturer. Type and concentration of extraction solvent used and herbal drug to extract ratio. Use latin binomial (capitalized genus name, lower case species name; both italicized) Challenges apply when doing a review on an herbal that has multiple species (ex. Echinacea) or when there are different dosage forms, species, doses, etc.
