PCTH 201 Lecture Notes - Lecture 8: Dysphoria, Clinical Trial, Chemotherapy-Induced Nausea And Vomiting
8 Oct 2017
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Document Summary
Cannabis: annual herbaceous (relating to herbs) plant genus grown in temperate and tropical climates, major species: c. indica and c sativa. Variety of alternate strains and/or hybrid subspecies. Vary in morphology, conditions for best growth, and pharmacodynamics. Cannabinoids: organic substances within c. spp, ~110 known phytocannabinoids, 3 of note: Phytocannabinoids: plant cannabinoids: thc is the only psychoactive constituent, cannabinol and cannabidiol both have some non-psychoactive physiological effects, to varying degrees. Fast-growing plant with vast industrial applications seeds and stalks: bad reputation by association with its more potent cousins, legality varies between different countries, often regulated based on thc concentration. Canada: [thc] < 10 ppm (10 g/g) ~8000 bc (late stone age): hemp fiber use. ~2700-2000 bce: psychotropic and therapeutic properties described in india and china. Relief of cramps, rheumatic and menstrual pain. ~ 1st century ce: taoists and cannabis seeds. 16th century ce: mention of medicinal effects start to appear in europe.
