BIOL 155 Lecture 19: BIOL 155 - Lecture 17 Notes

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9 Nov 2018
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Ubc biol 155 lecture 17 notes reproductive system. Hormonal regulation of male reproductive function: brain-testicular axis. Spermatogenesis is under hormonal control and involves interactions between the hypothalamus, anterior pituitary gland and the testes, a relationship sometimes called the brain-testicular axis. Recall that the hypothalamus produces a hormone called gonadotropin-releasing hormone (gnrh), which controls the release of a pair of anterior pituitary hormones called gonadotropins. The gonadotropins are the luteinizing hormone (lh) and the follicle-stimulating hormone (fsh) Lh binds to interstitial cells in the testes, cells found between the sperm-producing seminiferous tubules, and stimulates them to secrete testosterone (t). Most of t diffuses through to the seminiferous tubules while the rest enters the general circulation. Fsh, on the other hand, stimulates the sertoli cells of the seminiferous tubules to release a protein called androgen-binding protein (abp) Abp binds to t, which increases concentration of t within the testes. T stimulates and is absolutely required for spermatogenesis.

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