GERON255 Lecture 23: Lecture 23 – GERON 255

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Calcium: diet or supplements 1500 mg/day are recommended for post- menopausal women, leafy greens, sardines, salmon. Vitamin d: decreased absorption in ca in men and women but vitamin d helps with this, 400 iu/day too much is toxic. Estrogen: essential for maintenance of bone matrix, decreased levels makes bones more susceptible to pth, estrogen therapy for post-menopausal women, mixing estrogen with progesterone decreases risk of uterine and breast cancer. Calcitonin treatments: injectable for post-menopausal women, expensive and only replaces bone in first year. Exercise: weight bearing activities are advantageous, begin before age 35 preferably, increased risk with decreased levels of activity, it slows the rate of calcium loss but does not halt it entirely in elders. Function in homeostasis: smooth functioning of skeletal system of body, protects bones from traumatic injury by absorbing shock. Hyaline most common, in most joints: 2.

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