PHRM 221 Lecture Notes - Lecture 3: Coagulation, Vesicle Fusion, Extracellular Fluid
Document Summary
Requirements range from 200-1300 mg/day of elemental calcium from all sources (depending on age, gender, status) Dietary calcium : milk and dairy products , green leafy veggies, salmon, sardines. Ca2+ levels in blood and extracellular fluid (ecf) must be maintained within very narrow limits to support normal physiological functions. By active vit d-dependent transport and facilitated diffusion. Efficiency increases as intake decreases, in part due to activation of vit d. Storage controlled by vit d and parathyroid hormone (pth) Ecf ca2+ maintained largely by regulation of intestinal absorption and urinary excretion . However, if not adequate to maintain levels, ca2+ will be released from bone. Inadequate intake is common across all age groups. Not associated with any obvious short-term consequences. May contribute to accelerated bone loss and development of osteoporosis. If chronic, may prevent attainment of peak bone mass. Ul for calcium: ranges from 1000 mg/day (infants) to 3000 mg/day in adolescents.
