BIOL355 Lecture Notes - Lecture 28: Medullary Cavity, Ultimate Tensile Strength, Bone Marrow

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Structure of bone and cartilage: skeletal system: 2 major components, bones. Chemical composition of bone: organic, cells (osteoclasts, osteoblasts, osteocytes, matrix: collagen fibers, glycoproteins and proteoglycans, fibers secreted by osteoblasts, gives bone flexibility, tensile strength, withstand twisting. Inorganic: rigid, hard, able to withstand compression, 4x the strength of concrete, calcium crystals lie amongst and coat fibers of matrix. 2/3 of bone is mineral salts (calcium, phosphate, sodium, potassium: balance is essential, remove minerals bone becomes weaker (rubbery, remove collagen and bones brittle as glass. Anatomy: spongy bone: (red marrow, site of rbc formation in certain types of bones, very soft, porous in nature, diaphysis, contains medullary cavity, filled with yellow marrow (high in fat, capable of rbc formation under. Severe conditions: compact bone, very hard, forms outer layer of bone. Osteoblasts: synthesize collagen fibers + coat with minerals, build bone, repair bone, store excess minerals, result in [ca] in blood.

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