BIOL303 Lecture Notes - Lecture 6: Blastoderm, Vitelline Membrane, Polyspermy

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Drosophila eggs are activated as they pass through the oviduct independent of fertilization. Ca2+ channels are activated by the pressure on the egg as it passes through the oviduct. How might polyspermy be prevented in drosophila: drosophila does not have a cortical granule reaction since they have no cortical granules but changes in cortical cytoplasm are seen at egg activation (ie. cortical microtubules depolymerize). When the nuclei migrate to the cortex and undergo three additional cortical divisions, the syncytial blastoderm will form. What germ line related fates (ectoderm, mesoderm, endoderm) are associated with these features: mesoderm forms the ventral furrow, pinches off and becomes a tube. Endoderm invagination makes anterior and posterior midgut invaginations. Pole cells migrate into posterior midgut invagination (later they will squeeze through the midgut epithelium). Ectoderm and mesoderm undergo convergence and extension, movement toward posterior and ventral midline (known as germ band).

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