BIOL239 Lecture Notes - Lecture 2: Sickle-Cell Disease, Dihybrid Cross, Mendelian Inheritance

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Incomplete dominance: the f1 generation resembles neither purebred parent, rather, they show a mix of both (intermediate phenotype). Codominance: neither of the traits is dominant towards the other, but you see both traits in the offspring that are heterozygotes. Monomorphic: genes with only one wild-type allele. Polymorphic: genes with more than one wild type allele. Pleiotropic: multiple phenotypic effects caused by a single gene (i. e. sickle cell anemia). One gene, two alleles, changing many different phenotypes. Multifactorial inheritance: a phenotype arising from the action of two or more genes (polygenic) or from interactions between genes and the environment. Complementary gene action: two or more genes can work together in the same biochemical pathway to produce a particular trait. Heterogeneous trait: a mutation at any one of a number of genes can give rise to the same phenotype. Epistasis: a gene interaction in which the effects of an allele at one gene hides the effect of alleles at another gene.

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