BIOL130 Lecture Notes - Lecture 10: Spindle Apparatus, Golgi Apparatus, Kinesin
27 Feb 2015
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Network of fibres forming scaffolding within cytoplasm. Determines cell shape & position of organelles. Allows movement of cells themselves (motility) = flagella, cilia, lamellipodia. Cytoskeleton = dynamic (constantly being re-organized) = bones & muscles of cell. At first, cytoskeleton was only taught to be a feature of eukaryotes. However, recent advances in microscopy have shown that analogs of all major cytoskeletal elements exist in prokaryotes (similar role in eukaryotes: cell shape, cell division, cell polarity. Intestinal mucosal; made up of several cytoskeleton (villi) Creates a system of tracks for movement of vesicles/organelles. Reorganize themselves during mitosis to form mitotic spindle. Structures from which microtubules originate and radiate outward. Minus end of microtubule embedded in centrosomes (grow from ring) Bound to each other tightly (non-covalent bonds) Dimers polymerase = walls of hollow tube. Plus end = beta, minus end = alpha. Each tubule has polarity (plus and minus end)
