BIOL130 Lecture Notes - Lecture 3: Lipid Bilayer, Carboxylic Acid, Glycerol

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Lipids: group of carbon-containing compounds that are largely non-polar/hydrophobic (not water- soluble) Only macromolecule that is not a polymer. 3 major groups: fats/oil (triglycerides), sterols, phospholipids: triglycerides. Glycerol backbone + three fatty acid chains. Fatty acid chains form ester bond with oxygen on glycerol. Fatty acid have single (saturated) or double bonds (unsaturated) Ester linkages created between carboxyl on fatty acid and carbonyl on glycerol: phospholipids: have a hydrophilic region (polar head) and a very hydrophobic region (non-polar fatty acid tails) > thus allowing them to form lipid bilayer. Similar to triglyceride, but with one fatty acid replaced by a phosphate. Two of the oh- groups in glycerol are linked to fatty acids while third oh group is linked to phosphoric acid. Charged hydrophilic group bind to phosphate (polar head) Glycerol forms backbone of phospholipids (2 fatty acids + 1 phosphate group)

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