BIOL130 Lecture Notes - Lecture 5: Tryptophan, Cycloheximide, Francis Crick
12 Dec 2016
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Unit 5: gene expression dna to rna. Rna forms bonds with its own strand (base pairing between same strand) Many genes code for rna molecules that are not mrna. Involved in: regulation of gene transcription, processing of mrna prior to translation, translation. Types of rna rrna: form the core of the ribosome and catalyze protein synthesis. Mirna: regulate gene expression trna: serve as adaptors between mrna and amino acids during protein synthesis other small rna: rna splicing, telomere maintenance, etc. Transcription from a dna template formation of phosphodiester bonds. Only one strand of dna transcribed template strand. Other dna strand called non-template (coding) strand. E(cid:395)ue(cid:374)(cid:272)e of (cid:858)(cid:272)odi(cid:374)g(cid:859) dna st(cid:396)a(cid:374)d (cid:373)at(cid:272)hes na, t (cid:396)epla(cid:272)ed (cid:271)(cid:455) u. Formation of phosphodiester bonds (template strand and rna) Nucleoside triphosphate (ntp) monomers link with preceding one. Large, globular enzyme with several channels running through it. Active site is at the intersection of these channels.
