MBIO 2420 Lecture Notes - Lecture 31: Rna-Dependent Rna Polymerase, Nuclear Pore, Orthomyxoviridae
7 Dec 2016
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Cell type - where they stay latent. If virus infects it could lead to over proliferation of lymphocytes and get mono: population will remain after immune system attack and become latent. Latent phase: cell can differentiation and become a normal b cell, can also become a cell that cause burkitts lymphomas. Different herpes virus makes different proteins for latency and different outcomes can be caused. Ebna 1 and 2 are critical: maintain replication of latent genome. All viruses needed cellular ribosomes to make proteins. Replication is faster and more particles is made. All viruses must produce mrna that is then translated by cellular ribosomes. In this classification system, the unique pathways from various viral genomes to mrna define specific viral classes on the basis of the nature and polarity of their genome: draw this. Poxviruses excepted - they block nuclear pore complex: limited because they rely on the host so much.
