PATH 3610 Lecture Notes - Lecture 2: Amniotic Fluid Embolism, Hemoptysis, Etiology
16 Jun 2015
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Unit 2: changes in blood flow and body fluids. Introduction: one of the most common causes of cell degeneration and necrosis is a state of inadequate blood supply. Decreased synthesis (liver disease, protein malnutrition) Edema of congestive heart failure: effusion tissue fluid accumulates in body cavities (ex. Pleural space, pericardial sac, peritoneal cavity) (ex. Tissue colloid osmotic pressure increases, favors fluid remaining in tissue spaces. Plasma colloid osmotic pressure pull is not sufficient to move adequate amounts of fluid back into capillaries edema. Edema persists = edematous tissue may undergo fibrosis (affected area becomes firm and thickened) Two important causes of localized edema: venous obstruction, lymphatic obstruction. Two additional causes of local edema: acute inflammation (ex. Spider or insect bite: acute allergic reactions (ex. Outline how sodium and water retention exacerbates generalized edema. Fig 3- 3 (77): pathways leading to systemic edema due to heart failure, renal failure, or reduced plasma osmotic pressure.
