PATH 3610 Lecture Notes - Lecture 2: Disseminated Intravascular Coagulation, Oncotic Pressure, Shock Troops
24 Dec 2018
School
Department
Course
Professor
Document Summary
Unit 02: changes in blood flow and body fluid balance. Edema - the accumulation of fluid in the interstitium. In most normal tissues, the tissue hydrostatic and oncotic pressures are balanced and near zero, and as such contribute little to fluid exchange. Fluid movement between vascular and interstitial spaces governed by two opposing forces: vascular hydrostatic pressure, colloid osmotic pressure. In the normal capillary: at the arteriolar end of the capillary bed, fluid tends to move out of the capillaries because hydrostatic pressure (hp) exceeds the oncotic pressure (op). Oncotic pressure" or colloid osmotic pressure" refers to a form of osmotic pressure exerted by proteins, most notably albumin, within the plasma portion of blood. The pressure generated by the molecules usually draws water into vessel and hence the circulatory system. Accumulation of interstitial fluid within tissues; movement of fluid from vasculature into interstitial spaces; fluid may be protein poor (transudate) or protein rich (exudate)
