NUTR 3210 Lecture Notes - Lecture 12: Pentose Phosphate Pathway, Flavin Mononucleotide, Nicotinamide

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Micronutrients 3 micronutrients that act as enzyme cofactorsi. Niacin: term (cid:494)niacin(cid:495) is a generic term. Discovered through the condition pellagra in humans and a similar condition, called black tongues in dogs: niacin was considered the (cid:494)ant-black tongue(cid:495) factor. High incidence in areas where corn is the main dietary staple (because niacin is attached to indigestible chos in corn, this poorly absorbed. Most fish, meats, breads and cereals, coffee and tea. In coffee, trigonelline is converted to niacin by heat (i. e. , coffee bean roasting) In animal derived foods, vit b3 is commonly found as: In plant foods, vit b3 is predominantly found as nicotinic acid, which is considered a provitamin: niacin can also be produced in the liver from the amino acid tryptophan (but only 1/60th of trp is converted to niacin) /trp is another source that is taken into account when we start looking at dietary requirements. Digestion and absorption: digestion of nad and nadp is required before absorption.

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