NEUR 2000 Lecture Notes - Lecture 1: Camillo Golgi, Golgi'S Method, Reticular Theory

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The extraordinary complex shape and extensive branching caused difficulty of early research of individual neurons. Articulated and the championed the reticular theory of nerve cells communication: the idea that nerve cells directly connect with their neighbours, forming a continuous cell network or reticulum. Developed the golgi stain (nerve cells are stained black against a yellow background) Used golgi staining and light microscopy to draw nerve cells. Advocated the neuron doctrine: argued that neurons are discrete entities which communicate using specialized contacts that are not sites of continuity. Charles sherrington studied electrical signals in reflex pathways. Electron microscopes confirmed neurons to be independent units and the presence of synapses. Electron microscopes also showed intercellular continuities between some neurons (rare) knows as gap junctions. The cells of the nervous system can be divided into two broad categories: nerve cells (neurons, glial cells (neuroglia. Have the same basic structure as most other cells, including the cell body (soma) as well as other organelles.

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