MBG 3060 Lecture Notes - Lecture 26: Canis, Centimorgan, Marker-Assisted Selection
10 Apr 2018
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Document Summary
A chromosome region controlling (part of) a trait. It is not a gene but could be a gene. Find a polymorphism in the genome that is associated with a distinct difference in phenotype. Polymorphisms (alleles) need to be within the region of the genome that is of interest to use as markers. Molecular genetic tools used to find them. Highly polymorphic, expensive, variants depending on length. Mapping major genes with qualitative and quantitative effects. The first letter of genus + the first 2 letter of species. Hsa = homo sapien (human); ssc = sus scrofa (pig); bta = bos taurus (cattle); cfa = canis familiaris (dog); fca = felis catus (cat) The longer the dna is the more likely we are to observe less recombination rate than it actually is. If m1 and m2 recomb, and then m2 and m3 recomb, then there would appear to be no recomb has occurred between m1 and m3.
