BIOL 1090 Lecture Notes - Lecture 1: Histone H1, Metaphase, Nucleosome

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Dna and chromosome structure snustad & simmons, 6th ed. Funcions of the geneic material: the genotypic funcion replication, o the phenotypic funcion . Grown in presence of predators, developed to make it harder to eat. Genomes are not determinisic: interacions of genomes with environment (ex. Daphnia water leas: the evoluionary funcion mutation populaion variaion is the substrate on which natural selecion acts. At the heart of genes and geneics: dna. Each subunit is a nucleoide comprised of: phosphate group, 5 carbon sugar (2-deoxyribose, 1 of 4 cyclic nitrogenous bases. 4 nucleoides of dna: adenine, guanine, thymine, cytosine pyrimidines purine. Purine and pyrimidine nucleoide chains are connected by phosphodiester bonds. Dna strands are polar: 5 end free phosphate group, 3 end free hydroxyl group. The most common form of dna is called b=dna. There are two grooves of diferent width: major groove, minor groove. The irst level on condensaion packaging dna as a negaive supercoil into.

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