BIOL 1090 Lecture Notes - Lecture 15: Organelle, Ion, Glucose Transporter

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8 Mar 2016

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Lipids are absolutely essential to everything around us and can be thought of as the third genetic code. 3 classes of membranes: integral membrane proteins span the lipid bilayer, lipid-anchored proteins attach to a lipid in the bilayer, peripheral membrane proteins associate with the surfaces of the lipid bilayer. Biological membranes are asymmetrical: two leaflets have distinct lipid composition, in many plasma membranes, the outer leaflet contains glycolipids and glycoproteins. Proteins that penetrate the lipid bilayer ____: are called integrated proteins, may pass entirely through the lipid bilayer and protrude from both the extracellular and cytoplasmic sides of the membrane, are called lipid-anchored proteins, peripherally penetrated proteins. Structure of biological membranes: all membranes share common properties. Can be used to get medicine into a cell, should not be recognized by the white blood cells as they would then be destroyed. It will not change a) b) c: this situation does not apply to membranes.

Related Questions

Hybridomas are the useful result of a fusion between _______________ and _________________ to obtain hybrid cells that can proliferate and produce _________________ against specific ________________.

	myeloma cells; B lymphocytes; monoclonal antibodies; epitopes
	myeloma cells; T lymphocytes; polyclonal antibodies; antigen
	T lymphocytes; B lymphocytes; monoclonal antibodies; antigen
	T lymphocytes; B lymphocytes; polyclonal antibodies; epitopes

With respect to mammalian cell culture, which of the following statements is true?

	Media used for cell growth contain proteases and a divalent cation chelator to help cells adhere to the surface.
	During the establishment of a cell line, senescence is the last stage of the cell's life.
	Rodent cells cultures undergo spontaneous transformation with similar frequency to human cell cultures.
	Embryonic cell lines do not undergo senescence nor do they have a finite life span.

Epithelial cells have distinct surfaces. Which of these surfaces tends to be involved in secreting proteins out of the cell and into the bloodstream?

	apical
	basal
	All of the answers are correct.
	lateral

Which of the following is NOT true of phospholipid bilayers?

		Phospholipid bilayers separate the cell from the exterior environment as well as from compartments within the cell.
		The interior of phospholipid bilayers is a highly hydrophobic environment.
		Membrane budding requires transient breakages in the bilayer membrane.
		The chemical properties of phospholipids lead to the spontaneous formation of bilayers.

Which of the following is true regarding membrane proteins?

		All peripheral membrane proteins contact the lipid bilayer by covalent attachment to the hydrophilic head groups on membrane lipids.
		Beta strands can assemble into a membrane-spanning barrel structure.
		Lipid-anchored membrane proteins always face the cell exterior.
		A protein with six hydrophobic helices is most likely a lipid-anchored membrane protein.

Which of the following statements is NOT true?

		The three types of lipid anchors responsible for tethering proteins to the bilayer are acylation, prenylation, and ubiquitinylation.
		Movement of lipids from the cytoplasmic to the exoplasmic leaflet of the membrane bilayer requires specialized transport proteins called flippases.
		Glycoproteins are the basis for blood type compatibility between donor and receiver.
		Glycoproteins are always oriented so that the carbohydrate moieties are exoplasmic.

BIOL 1090 Lecture Notes - Lecture 15: Organelle, Ion, Glucose Transporter

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