BIOL 1080 Lecture Notes - Lecture 10: Natural Killer Cell, Sebaceous Gland, Lysozyme
Document Summary
Lecture #10-11 the local support and defense. The local support and defense system: nonspecific defenses innate immune system. First line of defense: nonspecific physical and chemical. Second line of defense: nonspecific internal cellular and surface barriers chemical defense: specific defenses. First line of defense external physical barriers: tears, skin: Provides a physical barrier to the entrance of microbes. Acidic ph discourages the growth of organisms. Sweat and oil gland secretions kill many bacteria. Normal bacterial inhabitants keep invaders in check. Washed microbes from the teeth and mucous membranes: large intestine, saliva: of the mouth, respiratory tract: Cilia sweep away trapped organisms: stomach, bladder: Second line of defense internal resident cells, proteins, inflammation and fever: identifies foreign (non-self) matter, but isn"t specific and doesn"t, defensive cells: develop a memory. Phagocytic cells such as neutrophils and macrophages. Kill many invading organisms and cancer cells: defensive proteins: Slow the spread of viruses in the body.