BIOC 2580 Lecture Notes - Lecture 10: Acetyl-Coa, Metabolic Pathway, Lecithin

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Protein acetate glucose fatty acids lecithin cholesterol mevalonate carotenoids. Anabolism = building up larger and more complex molecules from simple precursors. Catabolism = breakdown of large molecules and foodstuffs into simpler products. C skeletons of most sugars, fats, and aa are converted into a single metabolite. = leads to carrier of 2 c (acetate) units = acetyl coenzyme a (acetyl coa) Acetyl coa used to build everything from fas to steroids to components of proteins & nucleic acids. Converts precursor a product e through a series of intermediates (metabolites) Each step brings about a small and specific change. Get completely different product then what you started with. Irreversible at least 1 reaction is thermodynamically favorable (usually starter/drives pathway) Highly regulated transcriptional control of enzyme levels (slower) Inhibition or activation of enzyme activity (reversible phosphorylation) Removal, addition, transfer of a particular atom/functional gp. Biochemical genetics (genetic diseases, autotrophic mutants, transgenic organisms)

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