KNES 323 Lecture Notes - Lecture 6: Arteriosclerosis, Wound Healing, Ace Inhibitor

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F = p/r (flow rate of blood = change in pressure gradient / resistance of blood vessels) Driving pressure for systemic flow is created by lv. R depends on radius, length of vessel and blood viscosity. Distribution of blood sees muscle and skin take up most of the volume. Blood flow to the brain never decreases unless dying. Pulse pressure = systolic p diastolic p. Map = diastolic p + 1/3(systolic p diastolic p) Early- increase in thoracic pressure, ejection, bp and hr. Later- decrease in vr and sv and bp. Velocity of flow depends on total cross-sectional area of vessels. Baroreceptor reflex: (know reasons arterioles constrict or dilate!) Away from heart, pulsatile, high pressure, reinforced walls. These have more control over flow by vasoconstricting or dilating. When oxygen is high and co2 is low vasoconstriction. When oxygen is low and co2 is high, low sympathetic stimulation, etc. Thin enough for gas diffusion / nutrient exchange.

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