NURS215 Lecture Notes - Lecture 12: Coronary Artery Disease, Nitric Oxide, Hypertensive Crisis
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Ca(cid:396)dia(cid:272) disease is li(cid:374)ked to high (cid:271)od(cid:455) (cid:449)eight . Liquid calories are biggest culprit in weight gain. Portion control and diet diary are best solutions. 50% of intake should be fruits and vegetables. 5l (for kids by kilos, 80ml per kilo) Atrial stretch, when blood comes back, stretch gives body how much blood flow we have and pressure. Hormonal and nervous system factors influencing blood pressure. Diet (low sodium, less than 100 mg a day, healthy diet) Not first line therapy unless er: hypertensive emergencies & icu settings. Iv t1/2 = 2 minutes (iv infusion) inhalation (broncho-specific)) Hydralazine po/iv s/e: reflex tachycardia; hypotension!, syncope, headache. 4 types: loop, thiazides, potassium sparing, osmotic. Blocks na+, k+, cl- (nkcc2) re-absorption in loop of henle increased na, k, cl out. Drugs, (po): hydrochlorothiazide (hztz) chlorothiazide (diuril) metolazone (zaroxolyn) Decreases re-absorption of na from distal tubule increased na & k out (allows k out)